Ictal heart rate increase precedes EEG discharge in drug-resistant mesial temporal lobe seizures

Objective: Heart rate (HR) changes, mainly tachycardia, are often observed during seizures originating from the temporal lobe. The aim of this study was to analyze the role of ictal HR changes in localizing both mesial and lateral temporal lobe epilepsy (TLE) in a group of 68 patients. The influence of the gender and the side of epilepsy on HR modulation was also evaluated.

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Giancarlo Di Gennaro, Pier Paolo Quarato, Fabio Sebastiano, Vincenzo Esposito, Paolo Onorati, Liliana G. Grammaldo, Giulio N. Meldolesi, Addolorata Mascia, Carolina Falco, Ciriaco Scoppetta, Fabrizio Eusebi, Mario Manfredi, Giampaolo Cantore.