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Procedure to localize subdural electrodes

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Objectives: To evaluate a novel method for localization of subdural electrodes in presurgical assessment of patients with drug-resistant focal epilepsy.

Methods: We studied eight consecutive patients with posterior epilepsy in whom subdural electrodes were implanted for presurgical evaluation. Electrodes were detected on post-implantation brain CT scans through a semiautomated procedure based on a MATLAB routine. Then, post-implantation CT scans were fused with pre-implantation MRI to localize the electrodes in relation to the underlying cortical structures. The reliability of this procedure was tested by comparing 3D-rendered MR images of the electrodes with electrode position as determined by intraoperative digital photography.

F. Sebastiano, G. Di Gennaro, V. Esposito, A. Picardi, R. Morace, A. Sparano, A. Mascia, C. Colonnese, G. Cantore, P.P. Quarato