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Factors associated with generic and disease-specific quality of life in temporal lobe epilepsy

Purpose: We aimed at further elucidating the association between quality of life (QOL) and sociodemographic factors, clinical seizure factors, depression and anxiety in drug-resistant temporal lobe epilepsy (TLE).

Methods: We studied 106 consecutive adult right-handed patients (mean age 35.4±9.7; 50% males; IQ≥70) with drug-resistant unilateral (59% right) TLE (70% hippocampal sclerosis, 30% tumors or other lesions), who underwent a comprehensive noninvasive pre-surgical protocol.

Giulio N. Meldolesi, Angelo Picardi, Pier P. Quarato, Liliana G. Grammaldo, Vincenzo Esposito, Addolorata Mascia, Antonio Sparano, Pierluigi Morosini, Giancarlo Di Gennaro